Enalapril EP Impurity F HCl CAS 76391-34-9(Free Base)
| CAS No. | 76391-34-9(Free Base) |
| Molecular Formula | C22H32N2O5 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Enalapril EP Impurity F HCl (CAS 76391-34-9(Free Base)), a pharmacopoeial impurity reference standard (molecular formula C22H32N2O5HCl, MW 440.96 g/mol) used for the identification and quantification of trace impurities in APIs.
Enalapril EP Impurity F HCl (C22H32N2O5HCl) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Enalapril EP Impurity F HCl under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H32N2O5 HCl |
| Molecular Weight | 440.96 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Enalapril Standards
- Enalapril tert-Butyl Ester (CAS 108428-39-3)
- Enalapril Maleate Impurity 26 (CAS 115623-21-7)
- Enalapril EP Impurity D (CAS 115729-52-7)
- Enalapril-d5 tert-Butyl Ester (CAS 1356837-84-7)
- Enalapril-d3DISCONTINUED. Please see E555258 and E555252 (CAS 1356847-94-3)
- Enalapril EP Impurity A Maleate (CAS 1356932-13-2)
- Enalapril Impurity 19 (CAS 15121-89-8)
- Enalapril Impurity N1 (CAS 17450-56-5)
Recommended Standards
- Desogestrel EP Impurity B (CAS 54024-12-3)
- Rimegepant Impurity 100 (CAS CATO-C4X-2487100)
- Melatonin Impurity 22 (CAS CATO-C4X-229222)
- (1S)-1-Cyclopropyl-2,2-difluoro-ethanamine (CAS 2055389-19-8)
- (1-(2,2-Difluoroethyl)piperidin-4-yl)methanol (CAS 1249897-12-8)
- Canthin-6-one (CAS 479-43-6)
- Fortuneine (CAS 87340-25-8)
- N,2-dimethyl-4-(trifluoromethyl)thiazole-5-carboxamide (CAS 320420-66-4)
- 6-Chloro-1H-indole-2,3-dione 3-oxime (CAS 117886-84-7)
- Semaglutide impurity 272 (CAS CATO-C4X-2226272)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com